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Application of sodium metabisulfite in whitening skin care products

Time : 2021-04-21 Hits :

 

Potassium 4-Methoxysalicylate (4MSK) is a relatively novel whitening ingredient, similar in structure to salicylic acid, it inhibits melanin production and also promotes keratin metabolism. Due to the strong ionicity and discoloration of 4MSK, it is difficult to apply in formulations.
In order to design a stable whitening formula, in terms of color protection, antioxidants or sunscreens can be added to prevent 4MSK from discoloring. Antioxidants commonly used in whitening formulas include sodium metabisulfite, sodium bisulfite, vitamin E and its derivatives, etc.
Sodium metabisulfite is used more frequently in whitening formulas, and low doses have strong antioxidant properties.
Tests have shown that 4MSK has good thermal stability and poor light stability. Adding 0.2% pyrosulfinic acid can avoid the discoloration reaction of 4MSK.
When 4MSK is compounded with whitening agents, in terms of thermal stability, when the mass fraction of sodium metabisulfite is 0.05%, the thermal discoloration reaction of 4MsK with 3-O-ethyl ascorbic acid, niacinamide and tranexamic acid can be avoided.
Among them, the sodium metabisulfite required for the compounding of 4MSK and niacinamide is up to 0.01%.